ACME™ Biphenyl
ACME™ BIPHENYL
GET ALTERNATE SELECTIVITY AND BETTER RESOLUTION FOR REVERSED-PHASE ANALYSIS USING ACME BIPHENYL
ACME Biphenyl Key Features and Benefits:
• Reversed-phase retention similar to C18 columns
• Compatible with 100% aqueous mobile phases
• Orthogonal selectivity when compared to C18 columns
• Ideal for compounds that contain an aromatic (phenyl) group and exhibit π-π interaction
• Benzodiazepines, steroids, drugs of abuse (opiates, opioids, illicit drugs, tricyclic antidepressants, etc.), moderately polar analytes, i.e., alkenes, ketones, nitriles, etc.
• All HPLC and LC-MS applications where a C18 column does not provide sufficient selectivity
Selectivity Comparison Example of ACME Biphenyl vs. Standard C18
ACME Biphenyl, 3 μm, 100 x 2.1 mm ID
Standard C18, 3 μm, 100 x 2.1 mm ID
Isocratic Mobile Phase:
Acetonitrile:Water:Formic Acid, (37:63:0.1, v/v/v)
Flow rate: 0.3 mL/min
Temperature: 25 °C
Detection: UV@254 nm
Injection Vol.: 1 μL
Sample:
1. Oxazepam
2. Lorazepam
3. Nitrazepam
4. Alprazolam
5. Clonazepam
6. Temazepam
7. Flunitrazepam
8. Diazepam